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Kenneth W Mahaffey Selected Research

Renal Dialysis (Hemodialysis)

3/2024A Phase II randomized controlled trial evaluated antithrombotic treatment with fesomersen in patients with kidney failure on hemodialysis.
1/2023Defining myocardial infarction in trials of people receiving hemodialysis: consensus report from the SONG-HD MI Expert Working group.
12/2022Apixaban for Patients With Atrial Fibrillation on Hemodialysis: A Multicenter Randomized Controlled Trial.
7/2020A double-blind, randomized, placebo-controlled pilot trial to evaluate safety and efficacy of vorapaxar on arteriovenous fistula maturation.
3/2016Lessons Learned from EVOLVE for Planning of Future Randomized Trials in Patients on Dialysis.
7/2015Cinacalcet, Fibroblast Growth Factor-23, and Cardiovascular Disease in Hemodialysis: The Evaluation of Cinacalcet HCl Therapy to Lower Cardiovascular Events (EVOLVE) Trial.
6/2015Effects of Cinacalcet on Fracture Events in Patients Receiving Hemodialysis: The EVOLVE Trial.
5/2015The Effects of Cinacalcet in Older and Younger Patients on Hemodialysis: The Evaluation of Cinacalcet HCl Therapy to Lower Cardiovascular Events (EVOLVE) Trial.
5/2015Assessing the treatment effect in a randomized controlled trial with extensive non-adherence: the EVOLVE trial.
11/2014Effects of cinacalcet on atherosclerotic and nonatherosclerotic cardiovascular events in patients receiving hemodialysis: the EValuation Of Cinacalcet HCl Therapy to Lower CardioVascular Events (EVOLVE) trial.
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Kenneth W Mahaffey Research Topics

Disease

157Myocardial Infarction
04/2024 - 07/2001
151Hemorrhage
03/2024 - 12/2002
138Stroke (Strokes)
04/2024 - 12/2002
111Acute Coronary Syndrome
11/2022 - 07/2001
107Atrial Fibrillation
11/2023 - 06/2006
74Type 2 Diabetes Mellitus (MODY)
04/2024 - 05/2010
66Heart Failure
04/2024 - 06/2002
52Embolism (Embolus)
03/2024 - 06/2008
43Ischemia
03/2024 - 01/2002
43Thrombosis (Thrombus)
03/2024 - 06/2008
32Chronic Renal Insufficiency
04/2024 - 07/2008
32Cardiovascular Diseases (Cardiovascular Disease)
01/2024 - 11/2005
31Peripheral Arterial Disease
01/2023 - 07/2012
29ST Elevation Myocardial Infarction
01/2022 - 09/2003
20Albuminuria
01/2024 - 08/2016
17Infarction (Infarctions)
09/2013 - 01/2002
16Body Weight (Weight, Body)
01/2023 - 03/2010
15Diabetic Nephropathies (Diabetic Nephropathy)
01/2024 - 01/2019
14Ischemic Stroke
03/2024 - 09/2011
14Renal Insufficiency (Renal Failure)
03/2024 - 09/2010
14Kidney Diseases (Kidney Disease)
02/2024 - 07/2015
13Coronary Artery Disease (Coronary Atherosclerosis)
04/2024 - 07/2006
13Diabetes Mellitus
01/2022 - 06/2002
12Infections
01/2022 - 09/2003
12Transient Ischemic Attack
01/2022 - 02/2010
11Intracranial Hemorrhages (Intracranial Hemorrhage)
11/2023 - 02/2004
11Unstable Angina
01/2022 - 07/2001
10Chronic Kidney Failure (Chronic Renal Failure)
02/2024 - 12/2017
10Secondary Hyperparathyroidism
03/2016 - 09/2007
9Hypertension (High Blood Pressure)
01/2021 - 02/2010
7Coronary Disease (Coronary Heart Disease)
01/2023 - 06/2006
6Hemorrhagic Stroke
01/2019 - 10/2012
5Inflammation (Inflammations)
12/2021 - 10/2005
5Heart Diseases (Heart Disease)
12/2021 - 04/2006
5Stable Angina
11/2018 - 05/2012
5Sudden Death
01/2016 - 10/2012
5Shock
10/2013 - 09/2003
4Vascular Diseases (Vascular Disease)
11/2022 - 06/2006
4Cardiac Arrhythmias (Arrythmia)
10/2022 - 03/2012

Drug/Important Bio-Agent (IBA)

76CanagliflozinIBA
01/2024 - 08/2013
66Warfarin (Coumadin)FDA LinkGeneric
12/2022 - 02/2010
63Clopidogrel (Plavix)FDA Link
11/2022 - 05/2008
56RivaroxabanIBA
01/2022 - 06/2008
41Vitamin KFDA Link
01/2022 - 01/2013
39TicagrelorIBA
11/2022 - 09/2009
34CreatinineIBA
02/2024 - 06/2002
34cangrelorIBA
03/2022 - 12/2009
34Factor Xa (Coagulation Factor Xa)IBA
01/2022 - 02/2012
31AnticoagulantsIBA
11/2023 - 11/2003
26Enoxaparin (Lovenox)FDA LinkGeneric
12/2021 - 01/2003
25Glucose (Dextrose)FDA LinkGeneric
04/2024 - 07/2004
25Biomarkers (Surrogate Marker)IBA
01/2023 - 08/2005
24vorapaxarIBA
11/2022 - 03/2009
21SodiumIBA
04/2024 - 08/2013
21Thrombin Receptors (Thrombin Receptor)IBA
11/2022 - 01/2012
21Heparin (Liquaemin)FDA LinkGeneric
03/2019 - 12/2002
20Sodium-Glucose Transporter 2 InhibitorsIBA
04/2024 - 09/2015
20Glycoproteins (Glycoprotein)IBA
01/2020 - 04/2002
17Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
09/2017 - 09/2004
16omega-Chloroacetophenone (Mace)IBA
04/2024 - 12/2013
15Sodium-Glucose Transport ProteinsIBA
01/2024 - 03/2015
14AlbuminsIBA
11/2023 - 12/2017
14pexelizumabIBA
11/2013 - 09/2003
13SymportersIBA
04/2024 - 08/2013
12Complement System Proteins (Complement)IBA
04/2024 - 09/2003
11Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
01/2022 - 06/2006
11Cinacalcet (Sensipar)FDA Link
03/2016 - 09/2007
10MB Form Creatine KinaseIBA
10/2014 - 09/2003
9Factor Xa InhibitorsIBA
01/2020 - 07/2010
9StreptokinaseFDA Link
09/2019 - 02/2004
9Creatine Kinase (Creatine Phosphokinase)IBA
10/2014 - 08/2005
8AntithrombinsIBA
09/2010 - 12/2003
7TroponinIBA
01/2023 - 05/2007
6pro-brain natriuretic peptide (1-76)IBA
04/2024 - 04/2006
6apixabanIBA
12/2022 - 07/2010
6N(4)-oleylcytosine arabinosideIBA
01/2021 - 12/2016
6alirocumabIBA
12/2020 - 11/2014
6Tissue Plasminogen Activator (Alteplase)FDA Link
01/2018 - 08/2005
5Brain Natriuretic Peptide (Natrecor)FDA Link
04/2024 - 04/2006
5Glucagon-Like Peptide-1 Receptor AgonistsIBA
11/2023 - 11/2020
5Hemoglobins (Hemoglobin)IBA
01/2022 - 03/2008
5Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA
12/2021 - 12/2003
5Peptide Hydrolases (Proteases)FDA Link
07/2020 - 03/2014
5Anti-Arrhythmia AgentsIBA
01/2020 - 07/2013
5Platelet Membrane Glycoprotein IIbIBA
05/2015 - 12/2002
5Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA
03/2010 - 12/2002
4Mineralocorticoid Receptor AntagonistsIBA
11/2023 - 01/2018
4Growth Differentiation Factor 15IBA
11/2022 - 01/2014
4DiureticsIBA
10/2022 - 01/2021
4Insulin (Novolin)FDA Link
01/2022 - 03/2015

Therapy/Procedure

124Therapeutics
04/2024 - 07/2001
57Percutaneous Coronary Intervention
01/2023 - 09/2003
41Stents
03/2024 - 12/2003
25Coronary Artery Bypass (Coronary Artery Bypass Surgery)
01/2023 - 09/2004
16Surgical Amputation (Amputations)
03/2024 - 09/2007
14Renal Dialysis (Hemodialysis)
03/2024 - 09/2007
10Patient Readmission
03/2017 - 11/2005
9Secondary Prevention
01/2022 - 06/2008
8Blood Transfusion (Blood Transfusions)
01/2018 - 07/2004
6Thrombolytic Therapy
11/2017 - 12/2003